Big Nate: Genius Mode is a comic strip collection released on May 7, 2013.
- Nate claims he has a syndrome.
- Nate finds out Spitsy is half French Poodle.
- Nate sends a Valentine's cookie to Gina instead of Tina, which starts everyone thinking that Nate likes Gina.
- Marty Wright takes power yoga classes, and Nate uses this to help Ellen practice her laugh
- Jenny kissed Nate when they were younger, but Nate soon found out that Jenny kissed all the boys in the class.
- Teddy, Francis, and Nate build a treehouse, but they have never used it in any other comics.
- Nate decided that he won't do any schoolwork until high school, because he realized no one gets into college based on what they did in middle school.
- Artur, Francis, and Teddy all quit Enslave the Mollusk, leading to the collapse of the band.
- Nate learned hypnosis.
- Chad outsmarted Nate by pulling a wedgie on him on prank day.
- Nate is required to read one book a week due to his lousy report card, and he and his dad Martin Wright get together every week to discuss the books.